Anticoagulants
- Active ingredient (INN)
- pentoxifylline
- Composition (active ingredients)
- pentoxifylline - 100,0 mg
- Фармакотерапевтическая группа
- vasodilator
- Pharmacotherapeutic group
- enteric tablets, film-coated №60
- Сonditions of supply
- on prescription
Indications
Indications
- peripheral arterial occlusive disease of atherosclerotic or diabetic origin (eg, "intermittent" claudication, diabetic angiopathy)
- trophic disorders (for example, trophic ulcers of the legs, gangrene)
- cerebral circulation disorders (consequences of cerebral atherosclerosis, such as decreased concentration, dizziness, memory impairment), ischemic and post-stroke conditions
- circulatory disorders in the retina and choroid of the eye
- otosclerosis, degenerative changes against the background of vascular pathology of the inner ear and hearing loss
Dosage regimen
Dosage regimen
The dosage is set by the doctor in accordance with the individual characteristics of the patient. The drug should be swallowed whole during or immediately after a meal with plenty of water. The usual dose is: one tablet of pentoxifylline three times a day, followed by a slow increase in the dose to 200 mg 2-3 times a day. The maximum single dose is 400 mg. The maximum daily dose is 1200 mg.
- In patients with impaired renal function (creatinine clearance below 30 ml/min)
-
the dosage can be reduced to 1-2 tablets per day
- In patients with severely impaired liver function
-
dose reduction, taking into account individual tolerance
- In patients with low blood pressure, as well as in those at risk due to a possible decrease in blood pressure (patients with severe coronary artery disease (coronary artery disease) or with hemodynamically significant cerebral stenosis)
-
treatment can be started in small doses, the dose can only be increased gradually
Contraindications
There are contraindications, consult with a specialist before use
